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This platform seeks to provide the best possible support to improve both the health and economic outcomes from the COVID-19 pandemic. All contributions are welcome to better serve this goal. Please don't hesitate to send through relevant info using the form below. Before submitting, please make sure to check the accuracy of any information against reliable data sources, journals and other relevant publications.

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Chronology of Findings

Because of the volume of publications now coming out on COVID-19 - this list makes no attempt to be exhaustive. More articles can be found by checking out some of the links on our External Resources page. If you notice something missing, click the contribute button at the bottom of this page and let us know.

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May 12, 2020

Estimating 1-year Mortality

Taking into consideration all causes of death, estimated COVID-19 would cause 18,000 to 588,000 excess deaths in the UK depending how much of the population became infected.

Estimating Maternal & Child Mortality Indirect Impacts

Estimated even the best case scenario for the effects of COVID-19 could indirectly cause over 250,000 child deaths and 12,000 maternal deaths in low and middle income countries. Worst case this could be as high as 1.1 million child deaths and 56,000 maternal deaths.

May 11, 2020

Discussing Immunity Post-Infection

We don't yet know if you can achieve immunity.

May 7, 2020

Large study examining pre-dispositions to COVID-19 death

Analysis of deaths from 17 million NHS patients showed that males, those with existing conditions, and from asian or black ethnicities are more vulnerable to COVID-19.

April 29, 2020

First Treatment Discovered

A Remdesivir trial showed 31% time to faster recovery when using the drug

April 16, 2020

European Fatality + Demographics

Analysis of 21,522 fatalities in Europe showed 0.1% were below the age of 40. 12.8% were aged 40-69, and 84.8% were 70 years or older.

Italy Patient Details + Outcomes

A sample of 2,653 cases from Italy showed a mean age of 63.2 and a median time from symptom onset to diagnosis of 4 days. 40.5% were hospitalised and of those 37.4% had a comorbidity. 8.1% of cases died and for case that had up to 4 weeks of follow up this was higher. Comorbidities had a stronger association with mortality than with hospitalisation.

April 14, 2020

Iceland Demographic Findings

Iceland sample of 1,221 patients support findings children seem unlikely to contract COVID-19

April 13, 2020

No Pharmacologic Treatments shown effective to date

A literature review of existing pharmacologic research into COVID-19

April 10, 2020

Analysis of Chinese Fatalities from Jan

In a sample of 168 patients who died in China. The media age was 70. 95.8% were older than 50 years. 74.4% of patients had at least 1 comorbidity.

Heightened Neurologic Symptoms Present

36.4% of patients examined showed neurologic symptoms

April 8, 2020

Screening and Severity in Madrid Children

From a sample of 365 children tested in Madrid, 41 were found positive. 60% were hospitalised. 9.7% admitted to ICU. Only 1 child had a previous condition. No patients died.

Chinese effects of management outside of Hubei

Preparedness makes a big difference. Outside of Hubei Province where the disease originated, the rest of China was able to take measures to reduce the spread and mortality rates.

April 7, 2020

Even those classified as recovered could still be going home changed

Small study of 34 patients analyses various bio-markers and hints at impacts COVID-19 may have on additional organs such as the lever and heart. Analysis showed many biomarkers had not returned back to normal levels in those returning home.

April 6, 2020

Analysis of ICU patients in Italy

From a sample of 1591 critically ill patients in Lombardy, 99% required respiratory support. 88% intubation. Non-invasive ventilation 11%. ICU Mortality was 26% as of March 25.

April 3, 2020

Asymptomatic vs Pre-Symptomatic cases in a Washington cluster

A number of asymptomatic cases were identified in initial testing. Consecutive testing showed many of these went on to develop symptoms

April 2, 2020

Analysing transmission in China outside Hubei

Time to hospitalisation after symptom onset decreased from 4.4 days to 2.6 days as people became more familiar with the outbreak. The average time someone showed symptoms was 5.2 days. It took and estimated 3 weeks for China to get the disease below R1

WHO notes on Asymptomatic vs Pre-Symptomatic cases

There are few reports of laboratory confirmed cases who are truly asymptomatic. To date there has been no documented asymptomatic transmission. This doesn't mean that it isn't occurring.

March 31, 2020

Tasmania encourages parents to keep children from schools.

WA imposes internal travel restrictions.

March 30, 2020

Estimating COVID-19 severity from 37 countries

Average time till death after showing symptoms was 17.8 days and till hospital discharge 24.7 days. Crude fatality rate for China is estimated at 3.67% however after further adjustments and analysis the best estimate is 1.38%. Older age groups showed much higher fatality rates. Infection fatality ratio was estimated at 0.66%. Estimates of infected individuals likely to be hospitalised increased with age up 18.4%.

WA encourages parents to keep children from schools.

March 29, 2020

Australia limits all public gatherings to 2 people

March 27, 2020

Analysing an elderly cluster in Washington

Examination of a cluster of 167 cases coming out of long-term care facility in Washington showed hospitalisation rates around 50% and a fatality rate of 33.7%.

Australia makes quarantine mandatory for all new arrivals.

Australia asks only children of workers with no home care to attend school

March 26, 2020

Estimating Australian ICU beds needed

Based on overseas data and current trajectory, Australia should seek to control the spread of COVID-19 in order to ensure there are enough ICU beds available.

March 24, 2020

Japan postpones the Olympic Games.

Australia asks all citizens to stay at home unless for essential activities.

Victoria brings school holidays forward

ACT and NSW encourage parents to keep children from school

March 22, 2020

Australia closes pubs, cafes, gyms etc.

March 20, 2020

Australia implements 4m2 rule for indoor and outdoor gatherings

March 19, 2020

Estimating R0 and Asymptomatic likelihood

R0 estimated at 2.6. Genetic sequence analysis did not find evidence of a very large hidden burden of infection being debated at the time.

CT examining changes to the lungs

From a sample of 70 survivors, 94% of CT scans showed lung disease on discharge

Australia closes borders to all non-citizens and non-residents.

March 18, 2020

Comparing country readiness

Not all countries have the same capacity to defend again outbreaks. International Health Regulations are a set of regulations designed to align countries in a way that can help in events such as pandemics. This report looks at some aspects of how prepared different countries are

Australia limits public gatherings to 100 people indoors and 500 people outdoors.

March 16, 2020

Investigation of three clusters in Singapore

Symptoms confirmed similar to China data, incubation showing an average of 4 days and the serial interval between transmission pairs 3 and 8 days.

March 16, 2020

Australia limits public gatherings to 500 people

March 15, 2020

Australia extends self-quarantine advice to all arrivals.

March 13, 2020

First known USA person-to-person transmission

First US case passes infection on to husband but not others

The Melbourne Grand Prix is cancelled.

March 11, 2020

Early estimates on COVID-19 transmission and control

Estimate that the R0 for COVID-19 in China was 2.35 before travel restrictions and then moved down to 1.05 one week after. Estimated that once there was at least four independently introduced cases there was more than a 50% chance the infection will establish within that population.

Analysing mortality risk factors

Old people more vulnerable. People with comorbidities more likely to be hospitalised and result in fatalities. Average shedding of the virus for survivors was 20 days and COVID-19 was detectable until death in non-survivors. The longest observed viral shedding was 37 days. Viral shedding is associated with being infectious to others.  

Australia implements travel restrictions on arrivals from Italy

March 5, 2020

Australia implements travel restrictions on arrivals from South Korea

March 1, 2020

Australia implements travel restrictions on arrivals from Iran

February 28, 2020

WHO Report from Feb 16-24 Mission

WHO Report comes out with their initial epidemiological findings. Median age 51 years. R0 estimated at 2-2.5. Only 2.4% of cases below 18 years of age. Symptoms are said to be Fever and  Cough 87.9% and 67.7% of cases. Cases becomes symptomatic 5-6 days from infection. Approximately 80% have a mild disease, 13.8% severe and 6.1% critical. Whilst asymptomatic cases were reported the majority then went on to develop disease. True asymptomatic cases appears rare. Those above 60 years old and with comorbidities at risk. Fatality rate was 3.8% but varies by location. 5.8% in Wuhan and 0.7% in other parts of China. Mortality varied with age. 80 years 21.9%. Median time nationally from symptom onset to case confirmation came down from 12 days to 3 days by early Feb.  

Analysing feasibility of controlling COVID-19

The more infectious a disease the more important it is to contact trace and isolate. The delay between when a person notices symptoms and then how quickly they isolate made one of the biggest differences.

February 24, 2020

Examining critically ill patients in Wuhan

Looking at those who became critically ill, average wage was 59.7, 61.5% had died at 28 days. The average time from ICU admission to death was 7 days. Those who died were older - average age 64.9 years. 81% developed ARDS and 94% required ventilation. Most patients had organ function damage.

February 20, 2020

Early epidemiological analysis from China

Median age of patients was 46 years old. Few patients were younger than 15. Delays between symptom onset and seeking care in mainland China moved from 5 days to 2 days from Jan 18 to 31st.

Feb 17, 2020

China begins gradual return to work program

February 12-14, 2020

Wartime measures implemented in three cities in Hubei

Feb 1, 2020

Australia implements travel restrictions on arrivals from mainland China

January 31, 2020

Estimated COVID-19 domestic and international growth

Estimated the R0 to be 2.68 with 75,815 infected in Wuhan. The disease doubling every 6.4 days. Suggest the epidemics growing exponentially in multiple major cities of China with a lag behind Wuhan of 1-2 weeks.

January 30, 2020

Genomic characterisations of COVID-19

Virus genome shows dissimilarity from SARS-CoV and closest relationship to two Betacoronavirus found in bats back in 2018. Showed similar receptor bindings that contributed to making SARS-CoV dangerous.

Early epidemiological and clinic findings from Wuhan

49% of patients examined had a history of exposure to the Huanan seafood market. The average age was 55.5 years. 51% had chronic diseases. Symptoms showed fever and cough in 83% and 82% of cases. 75% showed pneumonia in both lungs. 17% developed ARDS. 11% patients died of multiple organ failure.

January 25, 2020

First confirmed case in Australia

January 24-25, 2020

Lockdown of 16 cities in Hubei

January 24, 2020

Clinical features of early COVID-19 patients

By Jan 2nd, 41 patients had been identified with COVID-19. 73% were men. 32% had underlying diseases. Median age was 49. 66% had been exposed to Huanan Seafood Market. Fever and cough showed up in 98% and 76% of cases respectively. 100% got pneumonia. 32% were admitted to ICU and 15% died.

Examination of an early family cluster

A family of 6 were found to have contracted COVID-19 between Dec 29 - Jan 4 and demonstrated person-to-person transmission. Throat swabs were negative but RT-PCR testing showed an unknown virus confirmed to be COVID-19. They showed symptoms 3-6 days after exposure.

January 23, 2020

Lockdown of Wuhan commences

January 22-23, 2020

First WHO Emergency Committee meeting

January 21, 2020

WHO Situation Report #1

First situation report published by WHO. 278 cases and 6 deaths

January 20, 2020

First case reported in the Republic of Korea and USA

China confirms human-to-human transmission

January 15, 2020

First case reported in Japan

January 13, 2020

First case reported in Thailand

January 13, 2020

First confirmed case in Nepal

January 12, 2020

COVID-19 Wuhan complete genome

China shares genetic sequence with the world temporarily named as '2019-nCov'

January 11-12, 2020

National Health Commission China conveys additional detailed information to WHO about an outbreak in Wuhan

January 11, 2020

First fatality in China

January 7, 2020

A new (Novel) Coronavirus is isolated and identified

January 1, 2020

Huanan Seafood Wholesale market closed

December 31, 2019

WHO China Country Office informed of cases of pneumonia from an unknown cause occurring in Wuhan City. 44 cases are reported to WHO over the next four days

December 30, 2019

Chinese officials begin searching for more cases

December 28-29, 2019

3 more cases of pneumonia from unknown origin are found in HICWM Hospital

December 27, 2019

Dr. Zhang reports unusual Pneumonia cases to the local CDC

December 26, 2019

4 unusual cases of Pneumonia noticed by Dr. Jixian Zhang in HICWM Hospital

December 8, 2019

1st known case of Pneumonia with unknown origin in Wuhan (identified retrospectively)

Source: JAMA timeline of initial events